› 4odb

X-ray diffraction
3.2Å resolution

Crystal structure of the T1L reovirus attachment protein sigma1 in complex with Junctional Adhesion Molecule-A

Released:
DOI: 10.2210/pdb4odb/pdb
PDB entry 4odb coloured by chain, front view.
PDB entry 4odb coloured by chain, side view.
PDB entry 4odb coloured by chain, top view.
Source organisms:
Entry authors: Stettner E, Stehle T

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137885 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Outer capsid protein sigma-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 165 amino acids
Theoretical weight: 18.79 KDa
Source organism: Mammalian orthoreovirus 1 Lang
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04506 (Residues: 308-470; Coverage: 35%)
Gene name: S1
Sequence domains: Reovirus viral attachment protein sigma 1
Structure domains: Virus attachment protein , globular domain
Junctional adhesion molecule A Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 104 amino acids
Theoretical weight: 11.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y624 (Residues: 28-129; Coverage: 38%)
Gene names: F11R, JAM1, JCAM, UNQ264/PRO301
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P3121
Unit cell:
a: 156.77Å b: 156.77Å c: 96.54Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.214 0.211 0.242
Expression system: Escherichia coli BL21(DE3)

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