› 4o4z

X-ray diffraction
1.7Å resolution

MURINE NEUROGLOBIN UNDER 30 BAR PRESSURE NITROUS Oxide

Released:
DOI: 10.2210/pdb4o4z/pdb
PDB entry 4o4z coloured by chain, front view.
PDB entry 4o4z coloured by chain, side view.
PDB entry 4o4z coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystallographic studies with xenon and nitrous oxide provide evidence for protein-dependent processes in the mechanisms of general anesthesia.
Abraini JH, Marassio G, David HN, Vallone B, Prangé T, Colloc'h N
Anesthesiology 121 1018-27 (2014)
PMID: 25211169

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190170 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuroglobin Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.31 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9ER97 (Residues: 1-151; Coverage: 100%)
Gene name: Ngb
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

3 bound ligands:
Ligand HEM 1 x HEM
Ligand SO4 1 x SO4
Ligand N2O 5 x N2O
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM16
Spacegroup: R32
Unit cell:
a: 89.275Å b: 89.275Å c: 114.765Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.173 0.172 0.188
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Neuroglobin: From structure to function in health and disease.
Ascenzi et al. (2016)
2 more