› 4nsx

X-ray diffraction
2.1Å resolution

Crystal Structure of the Utp21 tandem WD Domain

Released:
DOI: 10.2210/pdb4nsx/pdb
PDB entry 4nsx coloured by chain, front view.
PDB entry 4nsx coloured by chain, side view.
PDB entry 4nsx coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Structure of Utp21 tandem WD domain provides insight into the organization of the UTPB complex involved in ribosome synthesis.
Zhang C, Lin J, Liu W, Chen X, Chen R, Ye K
PLoS One 9 e86540 (2014)
PMID: 24466140

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170283 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
U3 small nucleolar RNA-associated protein 21 Chain: A
Molecule details ›
Chain: A
Length: 684 amino acids
Theoretical weight: 76.1 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q06078 (Residues: 1-684; Coverage: 73%)
Gene names: L8084.22, UTP21, YLR409C
Sequence domains: WD domain, G-beta repeat
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

1 bound ligand:
Ligand FLC 1 x FLC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P1
Unit cell:
a: 35.493Å b: 63.54Å c: 82.549Å
α: 110.95° β: 95.83° γ: 97.93°
R-values:
R R work R free
0.189 0.187 0.224
Expression system: Escherichia coli

Quick links

Citations

2 review citations

A Puzzle of Life: Crafting Ribosomal Subunits.
Kressler et al. (2017)
1 more

2 mentions without citation

UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly.
Hunziker et al. (2016)
1 more