4m1l

X-ray diffraction
2.1Å resolution

Complex of IQCG and Ca2+-bound CaM

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-143958 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 2-149; Coverage: 99%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair
Dynein regulatory complex protein 9 Chain: B
Molecule details ›
Chain: B
Length: 65 amino acids
Theoretical weight: 7.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H095 (Residues: 376-435; Coverage: 14%)
Gene names: DRC9, IQCG
Sequence domains: IQ calmodulin-binding motif

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P3221
Unit cell:
a: 40.491Å b: 40.491Å c: 179.689Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.189 0.187 0.228
Expression system: Escherichia coli