› 4lii

X-ray diffraction
1.88Å resolution

Crystal structure of an apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1) from Homo sapiens at 1.88 A resolution

Released:
DOI: 10.2210/pdb4lii/pdb
PDB entry 4lii coloured by chain, front view.
PDB entry 4lii coloured by chain, side view.
PDB entry 4lii coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132061 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apoptosis-inducing factor 1, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 513 amino acids
Theoretical weight: 56.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95831 (Residues: 100-611; Coverage: 84%)
Gene names: AIF, AIFM1, PDCD8
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand FAD 1 x FAD
Ligand EDO 2 x EDO
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 50.68Å b: 89.807Å c: 60.471Å
α: 90° β: 94.78° γ: 90°
R-values:
R R work R free
0.169 0.167 0.211
Expression system: Escherichia coli

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