› 4l4h

X-ray diffraction
2Å resolution

Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547

Released:
DOI: 10.2210/pdb4l4h/pdb
PDB entry 4l4h coloured by chain, front view.
PDB entry 4l4h coloured by chain, side view.
PDB entry 4l4h coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Kimlicka L, Tung CC, Van Petegem F

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123214 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ryanodine receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 547 amino acids
Theoretical weight: 61.58 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: E9Q401 (Residues: 1-547; Coverage: 11%)
Gene name: Ryr2
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand CL 1 x CL
Ligand PGE 1 x PGE
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P42212
Unit cell:
a: 78.04Å b: 78.04Å c: 248.38Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.22 0.251
Expression system: Escherichia coli BL21

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