› 4k7r

X-ray diffraction
2.09Å resolution

Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation

Released:
DOI: 10.2210/pdb4k7r/pdb
PDB entry 4k7r coloured by chain, front view.
PDB entry 4k7r coloured by chain, side view.
PDB entry 4k7r coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation.
Lei HT, Bolla JR, Bishop NR, Su CC, Yu EW
J Mol Biol 426 403-11 (2014)
PMID: 24099674

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160131 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation efflux system protein CusC Chain: A
Molecule details ›
Chain: A
Length: 446 amino acids
Theoretical weight: 49.39 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P77211 (Residues: 18-457; Coverage: 100%)
Gene names: JW0561, b0572, cusC, ibeB, ylcB
Sequence domains: Outer membrane efflux protein
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand 3PK 1 x 3PK
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: R32
Unit cell:
a: 89.026Å b: 89.026Å c: 474.103Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.214 0.25
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria.
Alav et al. (2021)
3 more

6 mentions without citation

Cu Homeostasis in Bacteria: The Ins and Outs.
Andrei et al. (2020)
5 more