› 4jpr

X-ray diffraction
2Å resolution

Structure of the ASLV fusion subunit core

Released:
DOI: 10.2210/pdb4jpr/pdb
PDB entry 4jpr coloured by chain, front view.
PDB entry 4jpr coloured by chain, side view.
PDB entry 4jpr coloured by chain, top view.
Source organism: Rous sarcoma virus (strain Schmidt-Ruppin A)
Primary publication:
Structural characterization of a fusion glycoprotein from a retrovirus that undergoes a hybrid 2-step entry mechanism.
Aydin H, Smrke BM, Lee JE
FASEB J 27 5059-71 (2013)
PMID: 24036886

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-237239 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ASLV fusion TM Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.71 KDa
Source organism: Rous sarcoma virus (strain Schmidt-Ruppin A)
Expression system: Escherichia coli BL21(DE3)
Structure domains: Helix Hairpins

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: R3
Unit cell:
a: 42.544Å b: 42.544Å c: 119.982Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.207 0.237
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Fusion of Enveloped Viruses in Endosomes.
White et al. (2016)
7 other articles

3 mentions without citation

A Frame-by-Frame Glance at Membrane Fusion Mechanisms: From Viral Infections to Fertilization.
Azimi et al. (2023)
2 more