› 4jjy

X-ray diffraction
6.5Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186719 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Programmed cell death 6-interacting protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 360 amino acids
Theoretical weight: 40.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WUM4 (Residues: 355-701, 702-708; Coverage: 41%)
Gene names: AIP1, ALIX, KIAA1375, PDCD6IP
Sequence domains: ALIX V-shaped domain binding to HIV

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: I23
Unit cell:
a: 223.77Å b: 223.77Å c: 223.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.203 0.283
Expression system: Escherichia coli

Quick links

Citations

17 review citations

The many functions of ESCRTs.
Vietri et al. (2020)
16 more

3 mentions without citation

Versatile roles of k63-linked ubiquitin chains in trafficking.
Erpapazoglou et al. (2014)
2 more