Function and Biology Details
Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130966 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear receptor coactivator 1; Retinoic acid receptor RXR-alpha
Molecule details ›
Chains: C, D
Length: 264 amino acids
Theoretical weight: 29.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Length: 264 amino acids
Theoretical weight: 29.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15788 (Residues: 678-700; Coverage: 2%) - Canonical: P19793 (Residues: 227-462; Coverage: 51%)
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Nuclear receptor coactivator 1; Nuclear receptor subfamily 1 group I member 2
Molecule details ›
Chains: A, B
Length: 336 amino acids
Theoretical weight: 38.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Length: 336 amino acids
Theoretical weight: 38.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O75469 (Residues: 130-434; Coverage: 70%)
- Canonical: Q15788 (Residues: 678-700; Coverage: 2%)
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
