› 4j4c

X-ray diffraction
1.9Å resolution

Structure of P51G Cyanovirin-N swapped dimer in the P3221 space group

Released:
DOI: 10.2210/pdb4j4c/pdb
PDB entry 4j4c coloured by chain, front view.
PDB entry 4j4c coloured by chain, side view.
PDB entry 4j4c coloured by chain, top view.
Source organism: Nostoc ellipsosporum
Primary publication:
Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Koharudin LM, Liu L, Gronenborn AM
Proc Natl Acad Sci U S A 110 7702-7 (2013)
PMID: 23610431

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160490 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyanovirin-N Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 10.98 KDa
Source organism: Nostoc ellipsosporum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P81180 (Residues: 1-101; Coverage: 100%)
Sequence domains: CVNH domain
Structure domains: Cyanovirin-N

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P3221
Unit cell:
a: 47.928Å b: 47.928Å c: 78.815Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.194 0.227
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Cyanobacterial lectins characteristics and their role as antiviral agents.
Singh et al. (2017)
3 more

1 mention without citation

Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Koharudin et al. (2013)