4j24

X-ray diffraction
2.1Å resolution

Estrogen Receptor in complex with proline-flanked LXXLL peptides

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-164596 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Estrogen receptor beta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 240 amino acids
Theoretical weight: 27.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92731 (Residues: 261-500; Coverage: 45%)
Gene names: ESR2, ESTRB, NR3A2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
19-mer peptide Chains: I, J, K, L
Molecule details ›
Chains: I, J, K, L
Length: 19 amino acids
Theoretical weight: 2.19 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: C2
Unit cell:
a: 192.98Å b: 53.49Å c: 131.39Å
α: 90° β: 120.47° γ: 90°
R-values:
R R work R free
0.192 0.19 0.224
Expression systems:
  • Escherichia coli
  • Not provided