› 4iua

X-ray diffraction
3.05Å resolution

Crystal Structure of the NK2 Fragment (31-290) of the mouse Hepatocyte Growth Factor/Scatter Factor

Released:
DOI: 10.2210/pdb4iua/pdb
PDB entry 4iua coloured by chain, front view.
PDB entry 4iua coloured by chain, side view.
PDB entry 4iua coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Tolbert WD, Zhou E, Kovach A, Melcher K, Xu HE

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-170591 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hepatocyte growth factor alpha chain Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 262 amino acids
Theoretical weight: 30.41 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08048 (Residues: 31-290; Coverage: 37%)
Gene name: Hgf
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand EPE 10 x EPE
Ligand SO4 15 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 92.62Å b: 127.328Å c: 129.6Å
α: 90° β: 90.25° γ: 90°
R-values:
R R work R free
0.183 0.176 0.245
Expression system: Escherichia coli

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