› 4hce

X-ray diffraction
2.3Å resolution

Crystal structure of the telomeric Saccharomyces cerevisiae Cdc13 OB2 domain

Released:
DOI: 10.2210/pdb4hce/pdb
PDB entry 4hce coloured by chain, front view.
PDB entry 4hce coloured by chain, side view.
PDB entry 4hce coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance.
Mason M, Wanat JJ, Harper S, Schultz DC, Speicher DW, Johnson FB, Skordalakes E
Structure 21 109-120 (2013)
PMID: 23177925

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152463 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell division control protein 13 Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 16.84 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P32797 (Residues: 344-495; Coverage: 17%)
Gene names: CDC13, YDL220C
Sequence domains: Cell division control protein 13, OB2 domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P212121
Unit cell:
a: 40.884Å b: 78.77Å c: 100.694Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.202 0.247
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Multiple facets of TPP1 in telomere maintenance.
Rajavel et al. (2014)
5 more

3 mentions without citation

Structure and function of the telomeric CST complex.
Rice et al. (2016)
2 more