› 4gwr

X-ray diffraction
1.81Å resolution

Crystal Structure of the second catalytic domain of protein disulfide isomerase P5

Released:
DOI: 10.2210/pdb4gwr/pdb
PDB entry 4gwr coloured by chain, front view.
PDB entry 4gwr coloured by chain, side view.
PDB entry 4gwr coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vinaik R, Kozlov G, Gehring K

Function and Biology Details

Reaction catalysed: 
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172190 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein disulfide-isomerase A6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 123 amino acids
Theoretical weight: 13.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15084 (Residues: 160-274; Coverage: 27%)
Gene names: ERP5, P5, PDIA6, TXNDC7
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P1
Unit cell:
a: 34.731Å b: 40.637Å c: 41.488Å
α: 93.43° β: 112.66° γ: 101.22°
R-values:
R R work R free
0.177 0.175 0.219
Expression system: Escherichia coli

Quick links