Function and Biology Details
Reaction catalysed:
5,10-methylenetetrahydrofolate + dUMP + NADPH = dTMP + tetrahydrofolate + NADP(+)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Flavin-dependent thymidylate synthase (preferred)
PDBe Complex ID:
PDB-CPX-194544 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Flavin-dependent thymidylate synthase
Molecule details ›
Chain: A
Length: 232 amino acids
Theoretical weight: 27.5 KDa
Source organism: Thermotoga maritima MSB8
Expression system: Escherichia coli
UniProt:
Sequence domains: Thymidylate synthase complementing protein
Structure domains: Gyrase A; domain 2
Length: 232 amino acids
Theoretical weight: 27.5 KDa
Source organism: Thermotoga maritima MSB8
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9WYT0 (Residues: 1-220; Coverage: 100%)
Sequence domains: Thymidylate synthase complementing protein
Structure domains: Gyrase A; domain 2
