Function and Biology Details
Reaction catalysed:
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Angiotensin-1 and Aminopeptidase N (preferred)
PDBe Complex ID:
PDB-CPX-133813 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Aminopeptidase N
Molecule details ›
Angiotensin-4
Molecule details ›
Chain: C
Length: 6 amino acids
Theoretical weight: 776 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 6 amino acids
Theoretical weight: 776 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
P01019 (Residues: 27-32; Coverage: 1%)
Ligands and Environments
Experiments and Validation Details
X-ray source:
CLSI BEAMLINE 08ID-1
Spacegroup:
P64
Expression systems:
- Homo sapiens
- Not provided
