Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Acriflavin resistance protein
- Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains
- RND efflux pump, membrane fusion protein
- RND efflux pump, membrane fusion protein, barrel-sandwich domain
- Cation efflux system protein CusB, domain 1
- Heavy metal binding domain
- Cation efflux system CusA-like
Structure analysis Details
Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153537 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cation efflux system protein CusB
Molecule details ›
Chains: B, C
Length: 413 amino acids
Theoretical weight: 45.18 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Length: 413 amino acids
Theoretical weight: 45.18 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P77239 (Residues: 1-407; Coverage: 100%)
Sequence domains:
- Cation efflux system protein CusB domain 1
- Heavy metal binding domain
- Long alpha hairpin domain of cation efflux system protein, CusB
Cation efflux system protein CusA
Molecule details ›
Chain: A
Length: 1054 amino acids
Theoretical weight: 115.73 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains: AcrB/AcrD/AcrF family
Length: 1054 amino acids
Theoretical weight: 115.73 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P38054 (Residues: 1-1047; Coverage: 100%)
Sequence domains: AcrB/AcrD/AcrF family
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Spacegroup:
R32
Expression systems:
- Escherichia coli BL21
- Escherichia coli
