Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Ephrin-A5 and Ephrin type-A receptor 4 (preferred)
PDBe Complex ID:
PDB-CPX-156647 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ephrin type-A receptor 4
Molecule details ›
Chain: A
Length: 568 amino acids
Theoretical weight: 62.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 568 amino acids
Theoretical weight: 62.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P54764 (Residues: 20-547; Coverage: 55%)
Sequence domains:
- Ephrin receptor ligand binding domain
- Tyrosine-protein kinase ephrin type A/B receptor-like
- Fibronectin type III domain
Ephrin-A5
Molecule details ›
Chain: C
Length: 180 amino acids
Theoretical weight: 20.69 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Ephrin
Structure domains: Cupredoxins - blue copper proteins
Length: 180 amino acids
Theoretical weight: 20.69 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P52803 (Residues: 27-166; Coverage: 67%)
Sequence domains: Ephrin
Structure domains: Cupredoxins - blue copper proteins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I24, DIAMOND BEAMLINE I04, DIAMOND BEAMLINE I04-1
Spacegroup:
R32
Expression system: Homo sapiens
