› 4ado

X-ray diffraction
2.3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184548 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FusB protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 26.31 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8GNY5 (Residues: 1-213; Coverage: 100%)
Gene names: far1, fusB
Sequence domains:
Structure domains: Monooxygenase

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P1
Unit cell:
a: 44.78Å b: 47.31Å c: 53Å
α: 89.87° β: 83.41° γ: 85.66°
R-values:
R R work R free
0.207 0.204 0.254
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

Ribosome-targeting antibiotics and mechanisms of bacterial resistance.
Wilson DN. (2014)
4 more

1 mention without citation

Structure and function of FusB: an elongation factor G-binding fusidic acid resistance protein active in ribosomal translocation and recycling.
Guo et al. (2012)