› 456d

X-ray diffraction
1.6Å resolution

MOLECULAR AND CRYSTAL STRUCTURE OF D(CGCGMO6AATCCGCG): THE WATSON-CRICK TYPE N6-METHOXYADENOSINE/CYTIDINE BASE-PAIRS IN B-DNA

Released:
DOI: 10.2210/pdb456d/pdb
PDB entry 456d coloured by chain, front view.
PDB entry 456d coloured by chain, side view.
PDB entry 456d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystallographic studies on damaged DNAs. I. An N(6)-methoxyadenine residue forms a Watson-Crick pair with a cytosine residue in a B-DNA duplex.
Chatake T, Ono A, Ueno Y, Matsuda A, Takénaka A
J Mol Biol 294 1215-22 (1999)
PMID: 10600379

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117161 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*CP*GP*(A47)P*AP*TP*CP*CP*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.68 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
1 modified residue:
Ligand A47 2 x A47

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6B, RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 25.1Å b: 39.9Å c: 65.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.196 0.231
Expression system: Not provided

Quick links

Citations

1 review citation

Promotion of rare nucleobase tautomers by metal binding.
Lippert et al. (2009)
11 other articles

1 mention without citation

DNA conformations and their sequence preferences.
Svozil et al. (2008)