› › Structure analysis

Crystal structure of BCL-XL in complex with inhibitor (WEHI-539)

X-ray diffraction
2.026Å resolution
PDB entry 3zlr coloured by chain, front view.
PDB entry 3zlr coloured by chain, side view.
PDB entry 3zlr coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Bcl-2-like protein 1
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 14505.46 Å2
Buried surface area: 4987.09 Å2
Dissociation area: 2,101.11 Å2
Dissociation energy (ΔGdiss): 34.58 kcal/mol
Dissociation entropy (TΔSdiss): 12.57 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-170525

Macromolecules

Bcl-2-like protein 1
Chains: A, B
Length: 158 amino acids
Theoretical weight: 17.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q07817 (Residues: 1-209; Coverage: 66%)
Gene names: BCL2L, BCL2L1, BCLX
Pfam:
InterPro:
Bcl-2-like protein 1 in PDB entry 3zlr, assembly 1, front view.
Bcl-2-like protein 1 in PDB entry 3zlr, assembly 1, side view.
Bcl-2-like protein 1 in PDB entry 3zlr, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links