› 3woz

X-ray diffraction
2.2Å resolution

Crystal structure of CLASP2 TOG domain (TOG3)

Released:
DOI: 10.2210/pdb3woz/pdb
PDB entry 3woz coloured by chain, front view.
PDB entry 3woz coloured by chain, side view.
PDB entry 3woz coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics.
Maki T, Grimaldi AD, Fuchigami S, Kaverina I, Hayashi I
J Mol Biol 427 2379-95 (2015)
PMID: 26003921

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183904 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CLIP-associating protein 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 232 amino acids
Theoretical weight: 26.98 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8BRT1 (Residues: 642-873; Coverage: 18%)
Gene names: Clasp2, Kiaa0627
Sequence domains: Centrosomal protein CEP104-like, TOG domain
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 28 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P21
Unit cell:
a: 50.896Å b: 122.317Å c: 86.514Å
α: 90° β: 94.67° γ: 90°
R-values:
R R work R free
0.243 0.241 0.279
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Nucleation and Dynamics of Golgi-derived Microtubules.
Sanders et al. (2015)
3 more

3 mentions without citation

CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics.
Maki et al. (2015)
2 more