Crystal structure of TNFalpha in complex with Adalimumab Fab fragment
The structure was published by Hu, S., Liang, S.Y., Guo, H., et al., Wang, H., Guo, Y.J., and Lou, Z.Y., in 2013 in a paper entitled "Comparison of the inhibition mechanisms of Adalimumab and Infliximab in treating TNFalpha-associated diseases from a molecular view" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.101 Å and deposited in 2013.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Tumor necrosis factor, Adalimumab Light Chain, and Adalimumab Heavy Chain.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: