spacer Crystal structure of TNFalpha in complex with Adalimumab Fab fragment
UniProt sequence   UniProt   CATH   Pfam   SCOP   Secondary structure   UniProt features   FASTA string  

Chain A: Tumor necrosis factor

1 V R S S S R T P S D K P V A H V V A N P Q A E G Q L Q W L N D R A N A L L A N G V E L R D N Q L V V P S E G L Y L I Y S
61 Q V L F K G Q G C P S T H V L L T H T I S R I A V S Y Q T K V N L L S A I K S P C Q R E T P E G A E A K P W Y E P I Y L
121 G G V F Q L E K G D R L S A E I N R P D Y L D F A E S G Q V Y F G I I A L

Regions

Secondary structure

Strand
Helix
Other

Chain H: Adalimumab Heavy Chain

1 E V Q L V E S G G G L V Q P G R S L R L S C A A S G F T F D D Y A M H W V R Q A P G K G L E W V S A I T W N S G H I D Y
61 A D S V E G R F T I S R D N A K N S L Y L D M N S L R A E D T A V Y Y C A K V S Y L S T A S S L D Y W G Q G T L V T V S
121 S A S T K G P S V F P L A P S S K S T S G G T A A L G C L V K D Y F P E P V T V S W N S G A L T S G V H T F P A V L Q S
181 S G L Y S L S S V V T V P S S S L G T Q T Y I C N V N H K P S N T K V D K K I

Regions

Secondary structure

Strand
Helix
Other

Chain L: Adalimumab Light Chain

1 D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I R N Y L A W Y Q Q K P G K A P K L L I Y A A S T L Q S G V P S
61 R F S G S G S G T D F T L T I S S L Q P E D V A T Y Y C Q R Y N R A P Y T F G Q G T K V E I K R T V A A P S V F I F P P
121 S D E Q L K S G T A S V V C L L N N F Y P R E A K V Q W K V D N A L Q S G N S Q E S V T E Q D S K D S T Y S L S S T L T
181 L S K A D Y E K H K V Y A C E V T H Q G L S S P V T K S F N R G E

Regions

Secondary structure

Strand
Helix
Other
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