Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
ORF169b and Ubiquitin-conjugating enzyme E2 N (preferred)
PDBe Complex ID:
PDB-CPX-158214 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ORF169b
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 24.12 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli
UniProt:
Sequence domains: Shigella glutamine deamidase OspI
Structure domains: Cathepsin B; Chain A
Length: 220 amino acids
Theoretical weight: 24.12 KDa
Source organism: Shigella flexneri
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8VSD5 (Residues: 1-212; Coverage: 100%)
Sequence domains: Shigella glutamine deamidase OspI
Structure domains: Cathepsin B; Chain A
Ubiquitin-conjugating enzyme E2 N
Molecule details ›
Chain: B
Length: 155 amino acids
Theoretical weight: 17.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ubiquitin-conjugating enzyme
Structure domains: Ubiquitin Conjugating Enzyme
Length: 155 amino acids
Theoretical weight: 17.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P61088 (Residues: 1-152; Coverage: 100%)
Sequence domains: Ubiquitin-conjugating enzyme
Structure domains: Ubiquitin Conjugating Enzyme
