› 3v2n

X-ray diffraction
1.8Å resolution

COMPcc in complex with fatty acids

Released:
DOI: 10.2210/pdb3v2n/pdb
PDB entry 3v2n coloured by chain, front view.
PDB entry 3v2n coloured by chain, side view.
PDB entry 3v2n coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The pentameric channel of COMPcc in complex with different fatty acids.
McFarlane A, MacFarlane AA, Orriss G, Okun N, Meier M, Klonisch T, Khajehpour M, Stetefeld J
PLoS One 7 e48130 (2012)
PMID: 23133613

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193082 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cartilage oligomeric matrix protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 45 amino acids
Theoretical weight: 5.24 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9R0G6 (Residues: 28-71; Coverage: 6%)
Gene name: Comp
Sequence domains: Cartilage oligomeric matrix protein
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

1 bound ligand:
Ligand MYR 1 x MYR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21
Unit cell:
a: 38.356Å b: 49.391Å c: 54.82Å
α: 90° β: 103.87° γ: 90°
R-values:
R R work R free
0.211 0.211 0.275
Expression system: Escherichia coli BL21

Quick links

Citations

4 citation in other articles

Oligomerization Affects the Ability of Human Cyclase-Associated Proteins 1 and 2 to Promote Actin Severing by Cofilins.
Purde et al. (2019)
3 more

2 mentions without citation

A Structural Analysis of Proteinaceous Nanotube Cavities and Their Applications in Nanotechnology.
Heide et al. (2022)
1 more