› 3ukn

X-ray diffraction
2.2Å resolution

Structure of the C-linker/CNBHD of zELK channels in C 2 2 21 space group

Released:
DOI: 10.2210/pdb3ukn/pdb
PDB entry 3ukn coloured by chain, front view.
PDB entry 3ukn coloured by chain, side view.
PDB entry 3ukn coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
Structure of the carboxy-terminal region of a KCNH channel.
Brelidze TI, Carlson AE, Sankaran B, Zagotta WN
Nature 481 530-3 (2012)
PMID: 22230959

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108809 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium voltage-gated channel, subfamily H (eag-related), member 3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 212 amino acids
Theoretical weight: 24.07 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A8WHX9 (Residues: 543-750; Coverage: 23%)
Gene name: kcnh3
Sequence domains: Cyclic nucleotide-binding domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2221
Unit cell:
a: 57.98Å b: 95.48Å c: 241.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.212 0.254
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Intracellular pH in sperm physiology.
Nishigaki et al. (2014)
14 more

7 mentions without citation

The enigmatic cytoplasmic regions of KCNH channels.
Morais-Cabral et al. (2015)
6 more