› 3uk3

X-ray diffraction
2.1Å resolution

Crystal structure of ZNF217 bound to DNA

Released:
DOI: 10.2210/pdb3uk3/pdb
PDB entry 3uk3 coloured by chain, front view.
PDB entry 3uk3 coloured by chain, side view.
PDB entry 3uk3 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vandevenne MS, Jacques DA, Guss JM, Mackay JP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116988 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Zinc finger protein 217 Chains: C, D
Molecule details ›
Chains: C, D
Length: 57 amino acids
Theoretical weight: 6.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75362 (Residues: 469-523; Coverage: 5%)
Gene names: ZABC1, ZNF217
Sequence domains: Zinc finger, C2H2 type
Structure domains: Classic Zinc Finger
5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3' Chain: A
Molecule details ›
Chain: A
Length: 20 nucleotides
Theoretical weight: 6.12 KDa
Source organism: Homo sapiens
Expression system: Not provided
5'-D(*AP*AP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP*CP*A)-3' Chain: B
Molecule details ›
Chain: B
Length: 20 nucleotides
Theoretical weight: 6.14 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand ZN 8 x ZN
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 124.67Å b: 40.98Å c: 52.04Å
α: 90° β: 97.21° γ: 90°
R-values:
R R work R free
0.225 0.224 0.256
Expression systems:
  • Escherichia coli
  • Not provided

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