Crystal structure of human menin in complex with MLL1
The structure was published by Huang, J., Gurung, B., Wan, B., et al., Merchant, J.L., Hua, X., and Lei, M., in 2012 in a paper entitled "The same pocket in menin binds both MLL and JUND but has opposite effects on transcription." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.0 Å and deposited in 2011.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Menin and Histone-lysine N-methyltransferase MLL.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: