› 3tlx

X-ray diffraction
2.75Å resolution

Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum

Released:
DOI: 10.2210/pdb3tlx/pdb
PDB entry 3tlx coloured by chain, front view.
PDB entry 3tlx coloured by chain, side view.
PDB entry 3tlx coloured by chain, top view.
Source organism: Plasmodium falciparum
Entry authors: Wernimont AK, Loppnau P, Crombet L, Weadge J, Perieteanu A, Edwards AM, Arrowsmith CH, Park H, Bountra C, Hui R, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + AMP = 2 ADP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184804 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate kinase 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 243 amino acids
Theoretical weight: 27.71 KDa
Source organism: Plasmodium falciparum
UniProt:
  • Canonical: Q8IJV6 (Residues: 1-242; Coverage: 100%)
Gene names: AK, AK1, PF3D7_1008900
Sequence domains:
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand MG 2 x MG
Ligand AMP 1 x AMP
Ligand ADP 3 x ADP
Ligand ATP 1 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 81.395Å b: 76.663Å c: 93.768Å
α: 90° β: 100.78° γ: 90°
R-values:
R R work R free
0.227 0.226 0.26

Quick links