Human Pin1 bound to trans peptidomimetic inhibitor
The structure was published by Zhang, M., Wang, X.J., Chen, X., et al., Ellington, A.D., Etzkorn, F.A., and Zhang, Y., in 2012 in a paper entitled "Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.267 Å and deposited in 2011.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1. This molecule has the UniProt identifier Q13526 (PIN1_HUMAN). The sample contained 158 residues which is 97% of the natural sequence. Out of 158 residues 145 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: