3sem Summary

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SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

The structure was published by Nguyen, J.T., Turck, C.W., Cohen, F.E., Zuckermann, R.N., and Lim, W.A., in 1998 in a paper entitled "Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 1998.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely SEX MUSCLE ABNORMAL PROTEIN 5 and SH3 PEPTOID INHIBITOR.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SEX MUSCLE ABNORMAL PROTEIN 5 P29355 (155-214) (SEM5_CAEEL)search Caenorhabditis eleganssearch < 90% 60 96%
B SEX MUSCLE ABNORMAL PROTEIN 5 P29355 (155-214) (SEM5_CAEEL)search Caenorhabditis eleganssearch < 90% 60 96%
C SH3 PEPTOID INHIBITOR Not available
Not available Not available 9 77%
D SH3 PEPTOID INHIBITOR Not available
Not available Not available 9 77%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P29355 (155 - 214) SEX MUSCLE ABNORMAL PROTEIN 5 Caenorhabditis elegans

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B SH3-domainsearch SH3 Domainssearch SH3 domainsearch
C, D
Chain InterPro annotation
A, B SH3 domainsearch Spectrin alpha chain, SH3 domainsearch
C, D