3s8r Summary

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PDB entry 3s8r (supersedes 1oqz)

Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation

The structure was published by Kim, J.K., Yang, I.S., Rhee, S., et al., Lee, Y.S., Park, S.S., and Kim, K.H., in 2003 in a paper entitled "Crystal structures of glutaryl 7-aminocephalosporanic acid acylase: insight into autoproteolytic activation." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2011.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Glutaryl-7-aminocephalosporanic-acid acylase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Glutaryl-7-aminocephalosporanic-acid acylase P07662 (30-720) (G7AC_PSEU7)search Pseudomonas sp. SY-77-1search 100% 697 98%
B Glutaryl-7-aminocephalosporanic-acid acylase P07662 (30-720) (G7AC_PSEU7)search Pseudomonas sp. SY-77-1search 100% 697 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P07662 (30 - 720) Glutaryl-7-aminocephalosporanic-acid acylase Pseudomonas sp. SY-77-1

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (P07662) Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1search, Penicillin Amidohydrolase, domain 1search, Penicillin amidase (Acylase) alpha subunit, N-terminal domainsearch PF01804: Penicillin amidasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P07662) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidessearch hydrolase activitysearch glutaryl-7-aminocephalosporanic-acid acylase activitysearch antibiotic biosynthetic processsearch response to antibioticsearch periplasmic spacesearch

Chain InterPro annotation
A, B Penicillin amidase-likesearch Penicillin/cephalosporin acylasesearch Penicillin amidase type, domain1search