spacer Crystal structure of CD4 mutant bound to HLA-DR1
CATH: Protein Structure Classification
CATH code 3.10.320.10 search
Domains
3s5lA01 , 3s5lD01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a, d.Fragment: mhc class ii a chain. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, e. Fragment: mhc class ii b chain. Synonym: mhc class iiantigen drb1*1, dr-1, dr1. Engineered: yes. Ha peptide. Chain: c, f.Fragment: ha peptide. Engineered: yes. T-cell surface glycoprotein cd4. Chain: g, h. Fragment: cd4. Synonym: t-cell surface antigen t4/leu-3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra, hla-dra1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Polymers A, D
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
3s5lA02 , 3s5lD02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a, d.Fragment: mhc class ii a chain. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, e. Fragment: mhc class ii b chain. Synonym: mhc class iiantigen drb1*1, dr-1, dr1. Engineered: yes. Ha peptide. Chain: c, f.Fragment: ha peptide. Engineered: yes. T-cell surface glycoprotein cd4. Chain: g, h. Fragment: cd4. Synonym: t-cell surface antigen t4/leu-3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra, hla-dra1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Polymers A, D
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
CATH code 3.10.320.10 search
Domains
3s5lB01 , 3s5lE01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a, d.Fragment: mhc class ii a chain. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, e. Fragment: mhc class ii b chain. Synonym: mhc class iiantigen drb1*1, dr-1, dr1. Engineered: yes. Ha peptide. Chain: c, f.Fragment: ha peptide. Engineered: yes. T-cell surface glycoprotein cd4. Chain: g, h. Fragment: cd4. Synonym: t-cell surface antigen t4/leu-3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra, hla-dra1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Polymers B, E
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
3s5lB02 , 3s5lE02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a, d.Fragment: mhc class ii a chain. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, e. Fragment: mhc class ii b chain. Synonym: mhc class iiantigen drb1*1, dr-1, dr1. Engineered: yes. Ha peptide. Chain: c, f.Fragment: ha peptide. Engineered: yes. T-cell surface glycoprotein cd4. Chain: g, h. Fragment: cd4. Synonym: t-cell surface antigen t4/leu-3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra, hla-dra1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Polymers B, E
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
CATH code 2.60.40.10 search
Domains
3s5lG01 , 3s5lG02 , 3s5lH01 , 3s5lH02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a, d.Fragment: mhc class ii a chain. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b, e. Fragment: mhc class ii b chain. Synonym: mhc class iiantigen drb1*1, dr-1, dr1. Engineered: yes. Ha peptide. Chain: c, f.Fragment: ha peptide. Engineered: yes. T-cell surface glycoprotein cd4. Chain: g, h. Fragment: cd4. Synonym: t-cell surface antigen t4/leu-3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra, hla-dra1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Polymers G, H
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
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