3s0z Summary

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Crystal structure of New Delhi Metallo-beta-lactamase (NDM-1)

The structure was published by Guo, Y., Wang, J., Niu, G., et al., Yang, C., Lou, Z., and Rao, Z., in 2011 in a paper entitled "A structural view of the antibiotic degradation enzyme NDM-1 from a superbug." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2011.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Metallo-beta-lactamase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Metallo-beta-lactamase E5KIY2 (47-270) (E5KIY2_ECOLX)search Escherichia colisearch < 90% 224 98%
B Metallo-beta-lactamase E5KIY2 (47-270) (E5KIY2_ECOLX)search Escherichia colisearch < 90% 224 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
E5KIY2 (47 - 270) Metallo-beta-lactamase Escherichia coli

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Metallo-beta-lactamase, chain Asearch Metallo-beta-lactamase superfamilysearch
Chain InterPro annotation
A, B Beta-lactamase-likesearch