Human Cytochrome P450 CYP17A1 in complex with Abiraterone
The structure was published by Devore, N.M. and Scott, E.E., in 2012 in a paper entitled "Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 2011.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Steroid 17-alpha-hydroxylase/17,20 lyase.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: