› 3rt6

X-ray diffraction
2.84Å resolution

Fluorowillardiine bound to the ligand binding domain of GluA3

Released:
DOI: 10.2210/pdb3rt6/pdb
PDB entry 3rt6 coloured by chain, front view.
PDB entry 3rt6 coloured by chain, side view.
PDB entry 3rt6 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Mechanisms of modal activation of GluA3 receptors.
Poon K, Ahmed AH, Nowak LM, Oswald RE
Mol Pharmacol 80 49-59 (2011)
PMID: 21464198

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148616 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 3 Chain: B
Molecule details ›
Chain: B
Length: 258 amino acids
Theoretical weight: 28.96 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P19492 (Residues: 417-530, 658-799; Coverage: 30%)
Gene names: GluA3, Glur3, Gria3
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand FWD 1 x FWD
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P2221
Unit cell:
a: 48.087Å b: 47.392Å c: 137.216Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.196 0.255
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Functional insights from glutamate receptor ion channel structures.
Kumar et al. (2013)
8 more

1 mention without citation

Mechanisms of modal activation of GluA3 receptors.
Poon et al. (2011)