› 3rd5

X-ray diffraction
1.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180990 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxidoreductase Chain: A
Molecule details ›
Chain: A
Length: 291 amino acids
Theoretical weight: 31.22 KDa
Source organism: Mycobacterium avium subsp. paratuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q741V7 (Residues: 1-289; Coverage: 100%)
Gene name: MAP_0980c
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

2 bound ligands:
Ligand EPE 1 x EPE
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G, RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 64.92Å b: 78.1Å c: 86.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.134 0.133 0.15
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Insights into multifaceted activities of CysK for therapeutic interventions.
Joshi et al. (2019)
5 more

6 mentions without citation

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells.
Abu-Remaileh et al. (2015)
5 more