3rat Summary

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EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K

The structure was published by Tilton Jr., R.F., Dewan, J.C., and Petsko, G.A., in 1992 in a paper entitled "Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 1991.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of RIBONUCLEASE A. This molecule has the UniProt identifier P61823 (RNAS1_BOVIN)search. The sample contained 124 residues which is 100% of the natural sequence. Out of 124 residues 124 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RIBONUCLEASE A P61823 (27-150) (RNAS1_BOVIN)search Bos taurussearch 90% 124 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P61823 (27 - 150) RIBONUCLEASE A Bos taurus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P61823) Ribonuclease A-likesearch P-30 Proteinsearch PF00074: Pancreatic ribonucleasesearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P61823) metabolic processsearch RNA phosphodiester bond hydrolysis, endonucleolyticsearch nucleic acid phosphodiester bond hydrolysissearch extracellular regionsearch nucleic acid bindingsearch hydrolase activitysearch protein bindingsearch pancreatic ribonuclease activitysearch endonuclease activitysearch nuclease activitysearch

Chain InterPro annotation
A Pancreatic ribonucleasesearch Ribonuclease A, active sitesearch Ribonuclease A-domainsearch