3r54 Summary

pdbe.org/3r54
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Human Cyclophilin D Complexed with a Fragment

A publication describing this structure is not available. The depositing authors are Colliandre, L.search; Ahmed-Belkacem, H.search; Bessin, Y.search; Pawlotsky, J.M.search; Guichou, J.F.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.35 Å and deposited in 2011.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Peptidyl-prolyl cis-trans isomerase F, mitochondrial. This molecule has the UniProt identifier P30405 (PPIF_HUMAN)search. The sample contained 166 residues which is < 90% of the natural sequence. Out of 166 residues 164 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Peptidyl-prolyl cis-trans isomerase F, mitochondrial P30405 (43-207) (PPIF_HUMAN)search Homo sapienssearch < 90% 166 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P30405 (43 - 207) Peptidyl-prolyl cis-trans isomerase F, mitochondrial Homo sapiens

Chain Sequence family (Pfam)
A Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLDsearch

Chain ID Molecular function (GO) Biological process (GO)
A (P30405) peptidyl-prolyl cis-trans isomerase activitysearch protein foldingsearch protein peptidyl-prolyl isomerizationsearch

Chain InterPro annotation
A Cyclophilin-type peptidyl-prolyl cis-trans isomerase domainsearch Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved sitesearch Cyclophilin-type peptidyl-prolyl cis-trans isomerasesearch Cyclophilin-like domainsearch