› 3r4a

X-ray diffraction
2.07Å resolution

Crystal structure of the 4-helix coiled coil CC-tet

Released:
DOI: 10.2210/pdb3r4a/pdb
PDB entry 3r4a coloured by chain, front view.
PDB entry 3r4a coloured by chain, side view.
PDB entry 3r4a coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
A de novo peptide hexamer with a mutable channel.
Zaccai NR, Chi B, Thomson AR, Boyle AL, Bartlett GJ, Bruning M, Linden N, Sessions RB, Booth PJ, Brady RL, Woolfson DN
Nat Chem Biol 7 935-41 (2011)
PMID: 22037471

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163967 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
coiled coil helix CC-tet Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 34 amino acids
Theoretical weight: 3.36 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: I222
Unit cell:
a: 44.73Å b: 50.9Å c: 103.06Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.209 0.27
Expression system: Not provided

Quick links

Citations

22 review citations

The coming of age of de novo protein design.
Huang et al. (2016)
21 more

11 mentions without citation

Strategies to control the binding mode of de novo designed protein interactions.
Der et al. (2013)
10 more