› › Structure analysis

MK2 kinase bound to Compound 1

X-ray diffraction
3Å resolution
PDB entry 3r2y coloured by chain, front view.
PDB entry 3r2y coloured by chain, side view.
PDB entry 3r2y coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: MAP kinase-activated protein kinase 2
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 13754.07 Å2
Buried surface area: 1380.93 Å2
Dissociation area: 521.57 Å2
Dissociation energy (ΔGdiss): -9.51 kcal/mol
Dissociation entropy (TΔSdiss): 5.42 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-155865

Macromolecules

MAP kinase-activated protein kinase 2
Chain: A
Length: 319 amino acids
Theoretical weight: 36.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P49137 (Residues: 46-364; Coverage: 80%)
Gene name: MAPKAPK2
Pfam: Protein kinase domain
InterPro:
CATH:
MAP kinase-activated protein kinase 2 in PDB entry 3r2y, assembly 1, front view.
MAP kinase-activated protein kinase 2 in PDB entry 3r2y, assembly 1, side view.
MAP kinase-activated protein kinase 2 in PDB entry 3r2y, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links