3qxa Summary details

spacer HLA-DR1 bound with CLIP peptide
Header IMMUNE SYSTEMsearch
Experiment Resolution: 2.712 Å, R-factor: 19.49%, Free R-factor: 23.49%, Spacegroup: P 21 21 21
Released 16/11/2011, deposition: 01/03/2011, last revision: 14/12/2011
Authors Painter, C.A.search; Stern, L.J.search
Primary citation Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange.
PROC.NATL.ACAD.SCI.USAsearch vol:108, pag:19329-19334 (2011) [PubMed 22084083 ]search
Keywords MHC class IIsearch, IMMUNE SYSTEMsearch
Organism Homo sapiens(human) 9606search(A D B E C F)
UniProt P01903search (A D)
P04229search (B E)
P04233search (C F)
Solvent A, B, C, D, E
Related entries 3qxd
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, D HLA class II histocompatibility antigen, DR alpha chain Protein P01903 (DRA_HUMAN)search
182 98%
B, E HLA class II histocompatibility antigen, DRB1-1 beta chain Protein P04229 (2B11_HUMAN)search
190 100%
C, F HLA class II histocompatibility antigen gamma chain peptide Protein P04233 (HG2A_HUMAN)search
15 93%