Thrombin Inhibition by Pyridin Derivatives
The structure was published by Biela, A., Khayat, M., Tan, H., et al., Heine, A., Hangauer, D., and Klebe, G., in 2012 in a paper entitled "Impact of ligand and protein desolvation on ligand binding to the S1 pocket of thrombin" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.63 Å and deposited in 2011.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Thrombin light chain, Thrombin heavy chain, and Hirudin variant-2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: