3qrr Summary


Structure of Thermus Thermophilus Cse3 bound to an RNA representing a product complex

The structure was published by Gesner, E.M., Schellenberg, M.J., Garside, E.L., George, M.M., and Macmillan, A.M., in 2011 in a paper entitled "Recognition and maturation of effector RNAs in a CRISPR interference pathway." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.099 Å and deposited in 2011.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Putative uncharacterized protein TTHB192 and RNA (5'-R(*GP*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP*GP*GP*(23G))-3').

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Putative uncharacterized protein TTHB192 Q53WG9 (1-211) (CAS6_THET8)search Thermus thermophilus HB8search 100% 267 76%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q53WG9 (1 - 211) Putative uncharacterized protein TTHB192 Thermus thermophilus HB8

Chain Structural classification (CATH) Sequence family (Pfam)
A (Q53WG9) Crispr-associated protein; domain 1search, Crispr-associated protein; domain 2search PF08798: CRISPR associated proteinsearch

Chain ID Molecular function (GO) Biological process (GO)
A (Q53WG9) RNA bindingsearch nuclease activitysearch endonuclease activitysearch hydrolase activitysearch metabolic processsearch defense response to virussearch nucleic acid phosphodiester bond hydrolysissearch

Chain InterPro annotation
A CRISPR-associated protein Cse3search