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Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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EC 3.6.4.12: DNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (DNA helix unwinding)
Alternative Name(s):
  • 3' to 5' DNA helicase
  • 3'-5' DNA helicase
  • 3'-5' PfDH
  • 5' to 3' DNA helicase
  • AvDH1
  • BACH1 helicase
  • BLM protein
  • BRCA1-associated C-terminal helicase
  • BcMCM
  • CeWRN-1
  • DNA helicase 120
  • DNA helicase A
  • DNA helicase E
  • DNA helicase II
  • DNA helicase III
  • DNA helicase RECQL5'
  • DNA helicase VI
  • Dbp9p
  • DmRECQ5
  • DnaB
  • DnaB helicase E1
  • HHcsA
  • HPif1
  • Hel E
  • Helicase DnaB
  • Helicase HDH IV
  • Helicase domain of bacteriophage T7 gene 4 protein helicase
  • Hmi1p
  • MCM helicase
  • MCM protein
  • MER3 helicase
  • MER3 protein
  • MPH1
  • PDH120
  • PIF1
  • PcrA
  • PcrA helicase
  • PfDH A
  • Pfh1p
  • UvrD

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF17981
Domain description: Cysteine Rich ADD domain
Occurring in:
  1. Transcriptional regulator ATRX
The deposited structure of PDB entry 3qla contains 2 copies of Pfam domain PF17981 (Cysteine Rich ADD domain) in Transcriptional regulator ATRX. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR011011
Domain description: Zinc finger, FYVE/PHD-type
Occurring in:
  1. Transcriptional regulator ATRX
IPR013083
Domain description: Zinc finger, RING/FYVE/PHD-type
Occurring in:
  1. Transcriptional regulator ATRX
IPR041430
Domain description: ATRX, ADD domain
Occurring in:
  1. Transcriptional regulator ATRX
IPR025766
Domain description: ADD domain
Occurring in:
  1. Transcriptional regulator ATRX

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