Function and Biology Details
Reactions catalysed:
GTP + H(2)O = GDP + phosphate
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate
1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 3,4-diphosphate + phosphate
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158164 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related protein Rab-8A
Molecule details ›
Chains: A, C, E, G
Length: 174 amino acids
Theoretical weight: 20.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 174 amino acids
Theoretical weight: 20.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P61006 (Residues: 6-176; Coverage: 83%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Inositol polyphosphate 5-phosphatase OCRL
Molecule details ›
Chains: B, D, F, H
Length: 140 amino acids
Theoretical weight: 16.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Inositol polyphosphate 5-phosphatase OCRL-like, ASH domain
Structure domains: Immunoglobulins
Length: 140 amino acids
Theoretical weight: 16.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q01968 (Residues: 540-678; Coverage: 15%)
Sequence domains: Inositol polyphosphate 5-phosphatase OCRL-like, ASH domain
Structure domains: Immunoglobulins
