3qbp Summary

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Crystal structure of fumarase Fum from Mycobacterium marinum

A publication describing this structure is not available. The depositing authors are Seattle Structural Genomics Center for Infectious Disease (SSGCID)search

This crystal structure was determined using X-ray diffraction at a resolution of 1.85 Å and deposited in 2011.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Fumarase Fum.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Fumarase Fum B2HT54 (1-474) (B2HT54_MYCMM)search Mycobacterium marinum Msearch 100% 478 93%
B Fumarase Fum B2HT54 (1-474) (B2HT54_MYCMM)search Mycobacterium marinum Msearch 100% 478 93%
C Fumarase Fum B2HT54 (1-474) (B2HT54_MYCMM)search Mycobacterium marinum Msearch 100% 478 93%
D Fumarase Fum B2HT54 (1-474) (B2HT54_MYCMM)search Mycobacterium marinum Msearch 100% 478 93%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
B2HT54 (1 - 474) Fumarase Fum Mycobacterium marinum M

Chain Sequence family (Pfam)
A, B, C, D (B2HT54) PF00206: Lyasesearch, PF10415: Fumarase C C-terminussearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B, C, D (B2HT54) lyase activitysearch fumarate hydratase activitysearch catalytic activitysearch tricarboxylic acid cycle enzyme complexsearch cytoplasmsearch fumarate metabolic processsearch tricarboxylic acid cyclesearch

Chain InterPro annotation
A, B, C, D Fumarate lyase familysearch Fumarate hydratase, class IIsearch L-Aspartase-likesearch Fumarase C, C-terminalsearch Fumarate lyase, conserved sitesearch Fumarate lyase, N-terminalsearch Fumarase/histidase, N-terminalsearch