Crystal structure of the ACVR1 kinase domain in complex with LDN-193189
The structure was published by Sanvitale, C.E., Kerr, G., Chaikuad, A., et al., Yu, P.B., Hill, C.S., and Bullock, A.N., in 2013 in a paper entitled "A new class of small molecule inhibitor of BMP signaling." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.82 Å and deposited in 2010.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Activin receptor type-1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: